Brenda Joyce DePolo Kludo passed away peacefully on July 6, 2022. She is survived by her husband Dr. Ronald G. Kludo, her brother, Rev. Frank DePolo and wife Becky, her son, Dr. Brent Morosco and wife Shannon, a daughter, Larrissa and husband Matthew Parks, nephews, Phil DePolo and Cindy, Jon DePolo and Janelle, and niece, Heather DePolo and Lynn. Brenda had many first cousins, nieces, and nephews. She also developed many close friendships over the years and loved every one of them. Brenda was preceded in death by her father Rev. John DePolo, and Doris DePolo, her mother. Brenda was a sweet, loving, and compassionate person, and by being a Christian, loved everyone she came into contact with during her life. Always smiling and engaged with her friends, she was uplifting and always positive. Brenda was a very successful person in many business ventures, her favorite being fashion. She opened a very successful boutique for high fashion in Beaver, PA. She wore many hats over the years and was a star in her field. She loved all people and will always be loved by those she touched. Family and friends will be received Sunday, July 10, 2022, 1:00 pm until 4:00 pm, and Monday, July 11th from 10:00 am until 2:00 pm, the time of service, in William G. Neal Funeral Homes, Ltd., 925 Allison Avenue, Washington, with Pastor Steven Parkhill officiating. Entombment to follow in Washington Cemetery Mausoleum. Memorial contributions may be made in Brenda’s memory to American Cancer Society, 320 Bilmar Dr, Pittsburgh, PA 15205.